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KMID : 0361519990100010057
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Korean Journal of Psychopharmacology
1999 Volume.10 No. 1 p.57 ~ p.64
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Clinical Features in Adult Schizophrenics with Minor Physical Anomalies
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Kang Dae-Yeob
Kang Seong-Suk
Chang Hi-Yeoul
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Abstract
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Objective：There have been several evidences that the central nervous system defect is one of the etiologic factor in schizophrenia and minor physical anomalies can reflect these defects indirectly. These central nervous defects are particularly related to the negative symptoms of schizophrenia. In this study, we examined the relationship between minor physical anomalies and psychopathology in schizophrenia.
Methods：Forty-four patients (22 males, 22 females) satisfying the DSM-IV criteria for schizophrenia were measured for minor physical anomalies by using Waldrop Anomaly Scale (WS) and we used Positive and Negative Syndrome Scale (PANSS), Ulmann-Giovannoni Process-Reactive Questionnaire (PRQ), and Phillips Premorbid Adjustment Scale (PAS) for evaluating psychopathology and clinical variables.
Results：Schizophrenic patients had a higher group mean WS score than that found in the control group. Score of WS was correlated with PANSS and PAS score positively, and with PRQ score negatively.
Conclusion：This study shows minor physical anomalies are associated with clinical variables with regard to symptom severity, poor premorbid adjustment and process of illness in at least some schizophrenics.
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KEYWORD
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Schizophrenia, Minor physical anomalies,
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